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    • Home
    • PROTEIN MAKER
    • 6-CHANNEL PM
    • PLUG MAKER
    • OPTI-MATRIX
    • SOFTWARE
    • ABOUT US
    • CONTACT
  • Home
  • PROTEIN MAKER
  • 6-CHANNEL PM
  • PLUG MAKER
  • OPTI-MATRIX
  • SOFTWARE
  • ABOUT US
  • CONTACT

Accelerate your research on protein function with parallel purification.  The Protein Maker workstation makes high throughput protein purification chromatography simple by allowing you to run 24 columns (1-5 mL or higher) in parallel, and process 96 samples unattended.  Protein Maker's flexible design allows you to customize sample and column types to achieve a variety of tasks:

  • Produce dozens of purified antibodies in a single day
  • Evaluate gene expression levels
  • Analyze functions of different isotypes or clones
  • Determine the best protein or enzyme purification method for scaling up
  • Screen constructs for protein structure studies

The new ProteinMaker 4.5 software has a simulation mode that lets researchers invent, test, edit, and archive new protein purification methods.   In addition, the software  includes modules for collecting and monitoring UV data, and gives scientists the ability to pause processes whenever they want.


Of course, the software  also provides full control over the instrument's syringe pumps, valves, and robotic XYZ gantry.  Proteinmaker 4.5 easily allows  the user to adapt the instrument to their unique needs.


Parallel Protein purification

  • Purify up to 192 protein samples per day
  • Fully automated: Set up and walk away
  • Customizable purification methods
  • Load wide range of volumes: a few mL or 1L+
  • Run 24 chromatography columns in parallel
  • 1-100+ mg scale purification

Applications

  • Antibody purification from 1L or larger starting volume
  • Risk-free purification scale-up through parallelization
  • Multi-construct design for structural biology
  • Lysis buffer scouting

OPERational modes

  • Production: 24 different protein samples, one type of chromatographic resin
  • Scouting: 24 different chromatographic resins, one protein sample
  • Multi-step: Automated, multi-column chromatography for up to 12 channels in parallel


links and documentation

  1. Protein Maker Brochure
  2. Protein maker Details and Specifications
  3. Peer-reviewed paper on Lysis Scouting in Acta Crystallography
  4. Parallelized Protein Purification.  Opportunities and Challenges in Early Stage Biotheraputics Research and Development.
  5. Application of the Protein Maker as a platform purification system for therapeutic antibody research and development.






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